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RESEARCH PRODUCT

Could isotretinoin be a protective agent against COVID-19?: A dermatologist perspective.

Selami Aykut TemizRecep DursunAnant PatilMohamad GoldustMichelangelo VestitaMichelangelo VestitaAyman AbdelmaksoudErhan Ayhan

subject

medicine.medical_specialtyskinCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Retinoic acidDermatologyProtective Agents030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCOVID‐19Acne VulgarismedicineHumansskin and connective tissue diseasesLetters to the EditorIsotretinoinContraindicationAcnebusiness.industrySARS-CoV-2COVID-19isotretinoinmedicine.diseaseDermatologyFirst line treatmentchemistry030220 oncology & carcinogenesisVero cellbusinessmedicine.drugDermatologists

description

Being a "trending" unique treatment for moderate-to-severe acne, isotretinoin (13-cis retinoic acid) (ISO) is currently considered by experts the first line treatment even for mild acne, unless there is an absolute contraindication. ISO was identified, among other retinoids, to inhibit SARS-CoV-2 replication in Vero E6 cells. Shoemark et al.1.

yearjournalcountryeditionlanguage
2021-06-06Journal of cosmetic dermatology
10.1111/jocd.14239https://pubmed.ncbi.nlm.nih.gov/34008285