6533b837fe1ef96bd12a28d4
RESEARCH PRODUCT
Osteogenic potential of a biosilica-coated P(UDMA-co-MPS) copolymer
Matthias WiensThomas NiemRenate SteffenUte SchloßmacherTarek A. ElkhoolyWerner E. G. M�llerSebastian Neumannsubject
Materials scienceCondensation polymerBiomedical EngineeringGeneral ChemistryGeneral Medicineengineering.materialMineralization (biology)UDMACoatingChemical engineeringPolymer chemistryengineeringCopolymerGeneral Materials Sciencedescription
A P(UDMA-co-MPS) copolymer was surface-functionalized through the polycondensation activity of the enzyme silicatein. The resulting biosilica coating significantly enhanced mineralization of osteoblastic cells, thereby revealing its osteogenic potential. Consequently, the functionalized copolymer may be explored as an alternative to conventionally used acrylics in applications where stable bone-material interfaces are required.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-04-09 | Journal of Materials Chemistry B |