6533b837fe1ef96bd12a33c5

RESEARCH PRODUCT

Near-Infrared, Light-Triggered, On-Demand Antiinflammatories and Antibiotics Release by Graphene Oxide/Elecrospun PCL Patch for Wound Healing

Nicolò MauroGennara CavallaroGaetano GiammonaSalvatore Emanuele Drago

subject

Ketoprofenvancomycinwound healing02 engineering and technology010402 general chemistry01 natural scienceslcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryIn vivopolycaprolactonemedicineFibroblastCell adhesionplasmaGeneral MedicineAdhesion021001 nanoscience & nanotechnologyon-demand drug release0104 chemical sciencesmedicine.anatomical_structurechemistryPolycaprolactoneBiophysicsgraphene oxide0210 nano-technologyWound healingCaprolactonemedicine.drug

description

Very recently, significant attention has been focused on the adsorption and cell adhesion properties of graphene oxide (GO), because it is expected to allow high drug loading and controlled drug release, as well as the promotion of cell adhesion and proliferation. This is particularly interesting in the promotion of wound healing, where antibiotics and anti-inflammatories should be locally released for a prolonged time to allow fibroblast proliferation. Here, we designed an implantable patch consisting of poly(caprolactone) electrospun covered with GO, henceforth named GO&ndash

yearjournalcountryeditionlanguage
2019-10-23
10.3390/c5040063http://hdl.handle.net/10447/377345