6533b838fe1ef96bd12a39f4

RESEARCH PRODUCT

Novel indole alkaloids from cell suspension cultures of aspidosperma quebracho blanco schlecht

Leo PolzHajime HosokawaHiromitsu TakayamaNaoki UchidaNaoko OhyaNorio AimiShin-ichiro SakaiLuis A. MendonzaJoachim Stöckigt

subject

Indole testchemistry.chemical_classificationMonoterpenoid Indole AlkaloidsbiologyChemistryStereochemistryAlkaloidOrganic Chemistrybiology.organism_classificationBiochemistrySuspension cultureTerpeneDrug DiscoveryAspidosperma quebracho-blancoOrganic chemistryLactone

description

Abstract Two novel monoterpenoid indole alkaloids, aspidochibine ( 1 ) and 3-oxo-14,15-dehydrorhazinilam ( 2 ), were isolated from cell suspension cultures of Aspidosperma quebracho blanco Schlecht. Aspidochibine ( 1 ) exhibits a new alkaloid skeleton. The structure of these alkaloids was elucidated by spectroscopic methods.

https://doi.org/10.1016/s0040-4039(00)93504-4