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RESEARCH PRODUCT
Reaction Condition Screening by Using Electrochemical Microreactor: Application to Anodic Phenol-arene C,C Cross-Coupling Reaction in High Acceptor Number Media
Toshio FuchigamiSiegfried R. WaldvogelMahito AtobeMahito AtobeBernd ElslerTsuneo Kashiwagisubject
ElectrolysisRenewable Energy Sustainability and the EnvironmentFormic acidInorganic chemistryCondensed Matter PhysicsAcceptorCoupling reactionSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialslaw.inventionchemistry.chemical_compoundAcetic acidchemistrylawMaterials ChemistryElectrochemistryPhenolMethanolMicroreactordescription
The anodic phenol-arene C,C cross-coupling reaction was achieved in inexpensive and sustainable media such as methanol, acetic acid, and formic acid by using an electrochemical microreactor which can provide a better performance to screen reaction conditions than in standard beaker-type electrolysis cells. Especially, formic acid as a reaction medium showed good performance. The total amount of cross-coupling product and homo-coupling products as a by-product was clearly increased as the solvent acceptor number increased. To control the selective oxidation of phenol, addition of methanol was effective.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 | Journal of The Electrochemical Society |