Synthesis of Natural Products By Rhodium-Mediated Intramolecular C-H Insertion

6533b838fe1ef96bd12a4593

RESEARCH PRODUCT

Synthesis of Natural Products By Rhodium-Mediated Intramolecular C-H Insertion

subject

chemistry.chemical_compound C c coupling Natural product chemistry Stereochemistry Intramolecular force Organic Chemistry chemistry.chemical_element General Chemistry Catalysis Natural (archaeology)Rhodium

description

The strategic advantages of the Rh-mediated intramolecular C–H insertion, which has been used as the key step in several natural product syntheses, are described here. The most recent such synthesis is the elegant route to (+)-morphine shown below.

year	journal	country	edition	language
1998-06-15	Chemistry - A European Journal

https://doi.org/10.1002/(sici)1521-3765(19980615)4:6<990::aid-chem990>3.0.co;2-u

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