6533b838fe1ef96bd12a5004
RESEARCH PRODUCT
Familial dyslexia: neurocognitive and genetic correlation in a large Finnish family.
Birgitta MyllyluomaTimo AhonenJuha KereJaana Nopola-hemmiArja VoutilainenSeija Leinonensubject
AdultMaleReading disabilitymedia_common.quotation_subjectNeuropsychological Testsbehavioral disciplines and activitiesDevelopmental psychologyDyslexia03 medical and health sciences0302 clinical medicineDevelopmental NeurosciencePhonological awarenessMemoryReading (process)mental disordersmedicineHumansChildFinlandmedia_commonLinkage (software)Language Disorders05 social sciencesDyslexiaNeuropsychology050301 educationmedicine.diseaseSpellingPedigreePediatrics Perinatology and Child HealthFemaleNeurology (clinical)PsychologyCognition DisordersNeurocognitive0503 education030217 neurology & neurosurgerydescription
Neuropsychological findings of individuals with dyslexia (n=24) from a large, three-generation Finnish family are presented. We have previously performed whole genome linkage scanning in this family and found that dyslexia in this kindred segregates with a single locus in the pericentromeric area of chromosome 3. Those included in the analyses were carefully evaluated for general cognitive ability, reading and spelling skills, and reading-related neurocognitive skills. The neurocognitive type of dyslexia segregating in this family consisted of deficits in phonological awareness, verbal short-term memory, and rapid naming. Severe dyslexia also seemed to be connected with a general language difficulty and was most common in the eldest generation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-02-13 | Developmental medicine and child neurology |