6533b839fe1ef96bd12a58ea

RESEARCH PRODUCT

<title>Influence of strong static magnetic field on human cancer HT 1080 cells</title>

Talivaldis FreivaldsIndulis BuikisTatjana IvanovaJuris RodinsVadims Korhovs

subject

MagnetismAcridine orangeCancerMagnetostaticsmedicine.diseasechemistry.chemical_compoundNuclear magnetic resonancechemistryCytoplasmCancer cellBiophysicsmedicinehuman activitiesHuman cancerTreated cell

description

The aim of this study was to investigate strong uniform magnetic field influence on the human cancer cells HT 1080. The cells were treated with magnetic field of intensity 1,16 Tesla and with anticancer agent - cis-platinum 0.025 mg/ml or vincristinum 2-3 ng/ml. The intact and the treated cell samples were incubated in a medium with acridine orange (AO). The magnetic field after 15 minutes of influence significantly increased cytoplasmic red fluorescence. Increased AO accumulation in lysosomes suggested to cancer cell metabolic activity stimulation.© (2001) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

https://doi.org/10.1117/12.447143