6533b839fe1ef96bd12a6089

RESEARCH PRODUCT

Thioflavin-T doped silica nanoparticles by basic-catalyzed sol-gel synthesis

Luisa SpallinoSimonpietro AgnelloMaurizio LeoneFranco Mario GelardiMarco CannasMg Di Carlo

subject

silica nanoparticleRaman spectroscopy.sol-gelThioflavin-Tdye-doping

description

We developed a basic-catalyzed sol-gel procedure that allows to synthesize silica nanoparticles functionalized with Thioflavin-T (ThT). During the synthesis, the formation of the doped silica nanoparticles was monitored by absorbance spectra indicating that the catalyst does not cause the total hydroxylation of the dye. Fluorescence measurements carried out on the ThT doped silica nanoparticles proved the attachment of ThT on silica and Raman spectroscopy provided information about the dye structure.

http://hdl.handle.net/10447/96820