6533b839fe1ef96bd12a66a9
RESEARCH PRODUCT
Aryl carbinols as nerve agent probes. Influence of the conjugation on the sensing properties
Santiago RoyoAna M. CosteroAna M. CosteroRaúl GotorRaúl GotorRamón Martínez-máñezSalvador GilSalvador GilFélix SancenónMargarita ParraMargarita Parrasubject
ChemistryChromogenicChemical warfare agentArylQUIMICA INORGANICAGeneral ChemistryCarbocationPhotochemistryCombinatorial chemistryChemical reactionCatalysisElimination reactionchemistry.chemical_compoundQUIMICA ORGANICAMethanol derivativeMaterials ChemistrymedicineElimination reactionAcetonitrilePhosphorylationAcetonitrileChemical reactionMolecular probeNerve agentmedicine.drugdescription
Two new aryl carbinols (1 and 3) have been synthesised and characterised and their ability as OFF-ON probes for the chromogenic detection of the nerve agent simulant in acetonitrile has been tested. In addition compound 2 has been also studied. The carbinols suffered a phosphorylation reaction followed by an elimination process giving rise to the corresponding carbocations. This transformation of the carbinol into the carbocation is responsible for a significant color change. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2012.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-04-13 |