6533b839fe1ef96bd12a6736

RESEARCH PRODUCT

The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review

Olivier HanonJean-sébastien VidalGeorge Pisica-donoseGaldric OrvoënJean-philippe DavidEdouard ChaussadeLaure CaillardLaura De JongNicolas BoullocheUlric VinsonneauStéphane BouéePierre Krolak-salmonLaurent FauchierPierre JouannyGuillaume SaccoFabienne BellarbreJoël BelminFrançois PuisieuxMatthieu LilamandElena PaillaudAnne Sophie BoureauAlban BelkoucheHermann YaoAlain PutotFrédéric ChaguéLuc RochetteNicolas DanchinMarianne ZellerYves Cottin

subject

medicine.medical_specialtylcsh:MedicineReview030204 cardiovascular system & hematologyCoronary artery embolism[SHS]Humanities and Social SciencesPathogenesis03 medical and health sciences0302 clinical medicineInternal medicinemedicineHospital dischargeatrial fibrillation030212 general & internal medicineMyocardial infarctionExcess mortalitychronic coronary syndromebusiness.industrylcsh:RAtrial fibrillationGeneral Medicinemedicine.diseasebleedingCoronary arteriesmedicine.anatomical_structuretype 1 and type 2 myocardial infarctionCardiology[SHS] Humanities and Social SciencesbusinessIschemic heart

description

International audience; This review was conducted to emphasize the complex interplay between atrial fibrillation (AF) and myocardial infraction (MI). In type 1 (T1) MI, AF is frequent and associated with excess mortality. Moreover, AF after hospital discharge for T1MI is not rare, suggesting the need to improve AF screening and to develop therapeutic strategies for AF recurrence. Additionally, AF is a common trigger for type 2 MI (T2MI), and recent data have shown that tachyarrhythmia or bradyarrhythmia could be a causal factor in, respectively, 13–47% or 2–7% of T2MI. In addition, AF is involved in T2MI pathogenesis as a result of severe anemia related to anticoagulants. AF is also an underestimated and frequent cause of coronary artery embolism (CE), as a situation at risk of myocardial infarction with non-obstructive coronary arteries. AF-causing CE is difficult to diagnose and requires specific management. Moreover, patients with both AF and chronic coronary syndromes represent a therapeutic challenge because the treatment of AF include anticoagulation, depending on the embolic risk, and ischemic heart disease management paradoxically includes antiplatelet therapy.

yearjournalcountryeditionlanguage
2021-01-07Journal of Clinical Medicine
10.3390/jcm10020198http://europepmc.org/articles/PMC7826531