6533b839fe1ef96bd12a679f
RESEARCH PRODUCT
Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR4-Like Resistance Island in Latvia
Mara SauleArnfinn SundsfjordArnfinn SundsfjordAija KarlsoneEdvins MiklasevicsUga DumpisNabil KarahNabil KarahØRjan SamuelsenArta Balodesubject
Acinetobacter baumanniiclone (Java method)Genomic IslandsMolecular Sequence DataMicrobial Sensitivity TestsIntegronbeta-Lactam Resistancebeta-LactamasesDisease OutbreaksIntegronsMicrobiologyMechanisms of ResistancePharmacology (medical)GeneVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical molecular biology: 711Sequence (medicine)PharmacologyCross InfectionMolecular EpidemiologyMolecular epidemiologyStrain (chemistry)biologyOutbreakMethyltransferasesVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical microbiology: 715biology.organism_classificationLatviaAnti-Bacterial AgentsBacterial Typing TechniquesAcinetobacter baumanniiInfectious DiseasesCarbapenemsVDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk immunologi: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk mikrobiologi: 715DNA Transposable Elementsbiology.proteinGenes MDRVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical immunology: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk molekylærbiologi: 711Acinetobacter Infectionsdescription
ABSTRACT An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla OXA-23 -positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacE Δ 1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼46,500 bp containing structures similar to the previously described AbaR22 and Tn 6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn 6022a interrupted by Tn 2006 carrying the bla OXA-23 gene.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 |