6533b83afe1ef96bd12a75ef

RESEARCH PRODUCT

Expression of a glucocorticoid receptor (D1GR1) in several tissues of the teleost fish Dicentrarchus labrax

Mirella VazzanaAiti VizziniGiuseppina SalernoDi Bella M. LMonica CeliNicolo' Parrinello

subject

StreDicentrarchus labraxGlucocorticoid receptorGlucocorticoid receptors; In situ hybridization; Immunohistochemistry; Stress; Dicentrarchus labraxIn situ hybridizationImmunohistochemistry

description

Since glucocorticoids have a role in maintaining the homeostatic status in fish, in the present paper mRNA expression (in situ hybridization) and tissue immunohistochemical localization of a glucocorticoid receptor (DlGR1) in several Dicentrarchus labrax organs are reported. Riboprobe and specific antibodies were prepared by using the DlGR1 that has been previously cloned and sequenced from peritoneal cavity leukocytes. Both mRNA and receptor were identified in head kidney, spleen, gills, intestine, heart and liver tissues. The functional roles of DlGR1 localization are discussed.

yearjournalcountryeditionlanguage
2008-01-01
10.1016/j.tice.2007.09.008http://hdl.handle.net/10447/14471