ChemInform Abstract: A Stereoselective Synthesis of (+)-Malyngolide via a Ring-Closing Olefin Metathesis.

6533b83afe1ef96bd12a7841

RESEARCH PRODUCT

ChemInform Abstract: A Stereoselective Synthesis of (+)-Malyngolide via a Ring-Closing Olefin Metathesis.

Miguel Carda J. Alberto Marco Santiago Rodriguez Encarnación Castillo

subject

chemistry.chemical_classification chemistry.chemical_compound Allylic rearrangement Ketone Chemistry Stereochemistry Stereoselectivity Malyngolide Erythrulose General Medicine Enantiomer Ring (chemistry)Metathesis

description

Abstract A very short and stereoselective synthesis of the non-natural enantiomer of malyngolide from l -erythrulose is described. Key features of the synthesis are the Felkin–Anh diastereoselective allylation of a polyoxygenated ketone and the allylation/metathesis/allylic oxidation protocol recently described by our group.

year	journal	country	edition	language
2000-10-10	ChemInform

https://doi.org/10.1002/chin.200041197

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