6533b83afe1ef96bd12a79ce

RESEARCH PRODUCT

2(S)-Amino-3-[1H-imidazol-4(5)-yl]propyl cyclohexylmethyl ether dihydrochloride and 2(S)-amino-3-[1H-imidazol-4(5)-yl]propyl 4-bromobenzyl ether dihydrochloride

Juhani HuuskonenJohannes A. M. ChristiaansJukka GyntherJari T. KovalainenElina Wegelius

subject

chemistry.chemical_compoundChemistryEtherGeneral MedicineCrystal structureMedicinal chemistryGeneral Biochemistry Genetics and Molecular BiologyHistamine

description

(Cyclohexylmethyloxymethyl)(1H-imidazol-4-iomethyl)-(S)-ammonium dichloride, C(13)H(25)N(3)O(+).2Cl(-), and (4-bromobenzyl)(1H-imidazol-4-iomethyl)-(S)-ammonium dichloride, C(13)H(18)BrN(3)O(+).2Cl(-), are model compounds with different biological activities for evaluation of the histamine H3-receptor activation mechanism. Both title compounds occur in almost similar extended conformations.

yearjournalcountryeditionlanguage
2000-05-15Acta Crystallographica Section C Crystal Structure Communications
https://doi.org/10.1107/s0108270100005291