Antioxidant capacity of trans -resveratrol dietary supplements alone or combined with the mycotoxin beauvericin

6533b83afe1ef96bd12a7ad7

RESEARCH PRODUCT

Antioxidant capacity of trans -resveratrol dietary supplements alone or combined with the mycotoxin beauvericin

Vincenzo Brandolini Annalisa Maietti Guillermina Font Paola Tedeschi María José Ruiz Beatriz Mallebrera

subject

Antioxidant viruses medicine.medical_treatment Resveratrol Toxicology 01 natural sciences Antioxidants NO Capillary electrophoresis Lipid peroxidation chemistry.chemical_compound 0404 agricultural biotechnology Depsipeptides Stilbenes medicine Food science Cytotoxicity Mycotoxin 010401 analytical chemistry virus diseases food and beverages 04 agricultural and veterinary sciences General Medicine Mycotoxins respiratory system Dietary supplements Beauvericin 040401 food science Beauvericin Antioxidant capacity 0104 chemical sciences Photochemiluminescence Antioxidant capacity chemistry Biochemistry Dietary supplements Beauvericin Resveratrol Antioxidant capacity Photochemiluminescence Capillary electrophoresis Resveratrol Polyphenol Food Science

description

Trans-resveratrol (trans-RSV) is a polyphenol with multiples biological properties, such as anti-inflammatory, antioxidant, anti-aging, anti-diabetic, and antiplatelet. It occurs naturally in grapes and derivate, peanuts and berries. Beauvericin (BEA) is a mycotoxin present in cereals that produces cytotoxicity, intracellular reactive oxygen species and lipid peroxidation. The general objective of this research was to evaluate whether trans-RSV could be used as a good polyphenol against damages produced by BEA. Because trans-RSV can be ingested through dietary supplements, to reach this goal, the following specific objectives were proposed: to determine a) the trans-RSV content in different polyphenol dietary supplements by capillary electrophoresis, b) the antioxidant capacity of the trans-RSV in polyphenol supplements, and c) the influence of BEA in the antioxidant capacity of trans-RSV when they are in combination by photochemioluminiscence assay. The results obtained in this study showed that all polyphenol dietary supplements present higher RSV content that the content of the label. The polyphenol supplements present antioxidant capacity. And the combination of trans-RSV and BEA did not affect the antioxidant capacity of trans-RSV. Thus, RSV could contribute to decrease oxidant effects produced by BEA.

year	journal	country	edition	language
2017-01-20	Food and Chemical Toxicology

https://doi.org/10.1016/j.fct.2017.04.027