6533b83afe1ef96bd12a7b48

RESEARCH PRODUCT

Effects of N2, O2'-dibutyril cyclic GMP on the nucleoside phosphotransferase activity of the retina of the chick embryos.

Giuseppe CalvarusoRenza VentoGiovanni Tesoriere

subject

PharmacologyRetinaNucleoside phosphotransferase activityPhosphotransferasesEmbryoCell BiologyChick EmbryoBiologyRetinaCellular and Molecular Neurosciencechemistry.chemical_compoundCyclic gmpmedicine.anatomical_structureBiochemistrychemistryNucleoside phosphotransferasemedicineMolecular MedicinePhosphorylationAnimalsThymidineMolecular BiologyNucleosideCyclic GMPThymidine

description

In the retina of the chick embryo, 2 different forms of nucleoside phosphotransferase take part in the phosphorylation of thymidine. One is an unstable form with higher molecular weight. The other with lower m. wt is a stable form. This paper shows that N2, O2′-dibutyril cyclic GMP causes a marked decrement of the activity of the unstable nucleoside phosphotransferase.

10.1007/bf01945928https://pubmed.ncbi.nlm.nih.gov/196899