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RESEARCH PRODUCT
Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study of 10 cases
Francesca BoggioNicola Adriano MonzaniMario CutroneAlessandro Del GobboCarlo GelmettiGiovanni FellegaraIsacco DebernardiLucia RestanoClaudio TripodoRaffaele GianottiEmilio BertiCristiana Colonnasubject
Pathologymedicine.medical_specialtySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virusesdermatopathology pediatric PLEVA SARS-CoV-2 skin histopathology Humans Pandemics SARS-CoV-2 COVID-19 Dermatitis PurpuraDermatitisDermatologySARS‐CoV‐2Eccrine glandMedicineHumansskin and connective tissue diseasesdermatopathologyPandemicsPurpuraHistological examinationbiologybusiness.industrySARS-CoV-2fungiskin histopathologyCOVID-19Original ArticlesNorthern italyStainingrespiratory tract diseasesbody regionspediatricPLEVAPediatrics Perinatology and Child Healthbiology.proteinImmunohistochemistryOriginal ArticleDermatopathologyAntibodybusinessdescription
Abstract We observed ten children with a papular eruption with purpuric features during the SARS‐CoV‐2 pandemic in Northern Italy (May‐December 2020). Histological examination showed signs of SARS‐CoV‐2‐related dermatosis. Evidence of nucleocapsid viral proteins using SARS‐CoV‐2 (2019‐nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-08-31 |