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RESEARCH PRODUCT
Broncalt®, class II medical device, in patients with acute upper airways disease: a survey in clinical practice.
Gian Franco CupidoMatteo GelardiIgnazio La MantiaSalvo Emanuele AragonaClaudio ViciniGiorgio Ciprandi Italian Study Group On Inflammatory Otorhinolaryngological Disorderssubject
AdultMaleupper airwaysAdolescentPlant ExtractsAcute disease; Grapefruit seed extract; Hyaluronic acid; Thermal water; Upper airwaysgrapefruit seed extractthermal waterWaterupper airways acute disease thermal water hyaluronic acid grapefruit seed extractNOOtolaryngologyOtorhinolaryngologic DiseasesYoung AdultTreatment OutcomeEquipment and SuppliesHealth Care SurveysAcute DiseaseSeedshyaluronic acidHumansFemaleOriginal ArticleCitrus paradisidescription
Inflammation is a common pathogenic mechanism involved in many otorhinolaryngological (ORL) disorders. Broncalt® is a class II Medical Device containing: thermal water (Medesano, PR, Italy), hyaluronic acid, and grapefruit seed extract. It has been reported that it exerted a safe and effective anti-inflammatory, washing, and antimicrobial activity by virtue of these components. Therefore, the aim of the current survey, conducted in clinical practice of 84 Italian ORL centers, was to evaluate its safety and efficacy in the treatment of patients with acute upper airways disease. The 3,533 (1,797 males, mean age 43.5 years) patients were evaluated at baseline (T0) and after a 2-week treatment (T1) with or without Broncalt®. Signs and symptoms severity were measured by visual analogue scale. Broncalt® significantly and safely diminished the clinical features in all sub-groups (p<0.001 for all). Interestingly, Broncalt®significantly induced a faster symptom relief already within 3 days after the start of the treatment. In conclusion, Broncalt® is a class II Medical Device able to exert a safe and effective activity in patients with acute ORL disorders. (www.actabiomedica.it)
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-07-03 | Acta bio-medica : Atenei Parmensis |