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RESEARCH PRODUCT

Tooth loss in Sjögren’s syndrome patients compared to age and gender matched controls

Tymour ForouzanfarJan WolffD. H. J. JagerHenk S. BrandFloor Maarse

subject

AdultMaleDentistryCohort StudiesAge and genderTooth LossSex Factorsstomatognathic systemPrevalencemedicineTooth lossHumansMaxillary central incisorGeneral DentistryAgedRetrospective StudiesAged 80 and overEdentulismOral Medicine and PathologyDentitionbusiness.industryResearchAge FactorsRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasestomatognathic diseasesSjogren's SyndromeOtorhinolaryngologyMaxillaUNESCO::CIENCIAS MÉDICASFemaleSurgerymedicine.symptombusinessCohort study

description

Background To analyze the prevalence and location of tooth loss in Sjögren’s syndrome (SS) patients and compare them with an age- and gender-matched control group. Material and Methods Dental charts and x-rays of 108 (SS) patients were retrieved from an academic dental center and special care dentistry department. For each SS patient, an age- and gender-matched non-SS patient was randomly selected. Medication, number of extractions and date and location of extractions were assessed. Differences between SS and non-SS patients were analyzed using Mann-Whitney U tests, Chi-square tests and Fisher’s exact tests. Results Significantly more SS patients were edentulous compared to the non-SS group (14.8% versus 1.9%, p = 0.001). SS patients had a 61% higher risk to have experienced one or more extractions than control patients. In the SS group, there was a non-significant tendency for more maxillary teeth to have been extracted than mandibular teeth (42:34). In the control group, the number of extractions in the maxilla and mandible were comparable (21:20). When divided into sextants, the number of SS patients with one or more extractions was significantly higher than for non-SS patients for each sextant (p = 0.001 to p = 0.032). The largest difference in the proportion of patients with one or more extractions between the SS and non-SS patients occurred in the upper anterior sextant (3.4 times more frequent). Conclusions SS patients are more prone to experience dental extractions compared to patients without SS. It could be speculated that this is related to a decreased salivary secretion. Key words:Sjögren’s syndrome, dentition, edentulism, extractions, dental health.

10.4317/medoral.22545https://research.vu.nl/en/publications/a628e8e1-f5ad-4bcd-bde1-78a4c6c7336c