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RESEARCH PRODUCT

Oxygen Transport in Tumors

Peter Vaupel

subject

Cervical cancerChemotherapyNormal oral mucosaTreatment modalitybusiness.industrymedicine.medical_treatmentCancer researchmedicineOxygen transportbusinessmedicine.diseaseCumulative frequency distribution

description

Experimental evidence suggests that the hypoxic fraction in solid tumors may influence its growth, may increase its malignant potential, and may reduce its sensitivity towards non-surgical treatment modalities (e.g., standard irradiation, certain anticancer drugs). The role of the tumor O2 status in radio-/chemotherapy and its impact on relevant tumor biological characteristics of tumors are summarized in Table 1.

https://doi.org/10.1007/978-1-4613-0333-6_44