6533b851fe1ef96bd12a8bde
RESEARCH PRODUCT
Papaverine in Human Bladder Muscle
H. NawrathL. Hertlesubject
Papaverinemedicine.medical_specialtyRelaxation (psychology)urogenital systembusiness.industryCorpus cavernosum penisHuman bladderUrologyUreteral stonemedicine.anatomical_structureMuscle stripUrological DisordersMedicineExtracellular potassiumbusinessmedicine.drugdescription
It is generally assumed that drugs which induce relaxation of smooth muscles may be of clinical importance in some urological disorders; such drugs are indeed widely used, for example, in the therapy of unstable bladders or to facilitate the passage of ureteral stones. Recently, papaverine has been shown to be very effective, e.g., in relaxing smooth muscles of the corpus cavernosum penis, thereby inducing erections in many impotent men (Virag 1982). The purpose of this study is to determine the relaxing properties of papaverine in isolated muscle strips from the human detrusor and to evaluate its potential clinical importance.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-01-01 |