6533b851fe1ef96bd12a8c59

RESEARCH PRODUCT

Evaluation of skin pathologies by RGB autofluorescence imaging

Alexey LihachevAlexander DerjaboIlze LihacovaMarta LangeEmilija Vija Plorina

subject

medicine.medical_specialtyLupus erythematosusHyperkeratosesintegumentary systembusiness.industryScarsVitiligomedicine.diseaseDermatologyAutofluorescencePurpuraPsoriasismedicineSkin cancermedicine.symptomskin and connective tissue diseasesbusiness

description

A clinical trial on autofluorescence imaging of malignant and non-malignant skin pathologies comprising 32 basal cell carcinomas (BCC), 4 malignant melanomas (MM), 1 squamous cell carcinoma (SCC), 89 nevi, 14 dysplastic nevi, 20 hemangiomas, 23 seborrheic keratoses, 4 hyperkeratoses, 3 actinic keratoses, 3 psoriasis, 1 dematitis, 2 dermatofibromas, 5 papillofibromas, 12 lupus erythematosus, 7 purpura, 6 bruises, 5 freckles, 3 fungal infections, 1 burn, 1 tattoo, 1 age spot, 1 vitiligo, 32 postoperative scars, 8 post cream therapy BCCs, 4 post radiation therapy scars, 2 post laser therapy scars, 1 post freezing scar as well as 114 reference images of healthy skin was performed. The sequence of autofluorescence images of skin pathologies were recorded by smartphone RGB camera under continuous 405 nm LED excitation during 20 seconds with 0.5 fps. Obtained image sequences further were processed with subsequent extraction of autofluorescence intensity and photobleaching parameters.

https://doi.org/10.1117/12.2297007