6533b851fe1ef96bd12a9945

RESEARCH PRODUCT

A new suggested class of organic tubular structures

Gianfranco La MannaFrancesco Ferrante

subject

Peptides Peptides Cyclic peptide nanotubechemistry.chemical_compoundCrystallographyMonomerChemistryStackingGeneral Physics and AstronomyPhysical and Theoretical ChemistryAntiparallel (biochemistry)

description

A DFT study has been performed on monomers and dimers of new cyclic structures, cyclodioxabislactams, which are expected to bring about tubular structures through a stacking process settled by hydrogen-bonding between antiparallel peptidic groups. Different stacking modes have been found with significant effects on the energetics of the assembling process.

https://doi.org/10.1016/j.cplett.2003.11.055