6533b851fe1ef96bd12aa0ee

RESEARCH PRODUCT

Quantitative Cerebral Blood Flow Mapping in Stroke and During Mental Stimulation After Intravenous Injection of 195mAu

P. LindnerO. Nickel

subject

Background subtractionbusiness.industryRadiation doseStimulation99mtc pertechnetatemedicine.diseaseShort lifeCerebral blood flowAnesthesiamedicineWhole bodyNuclear medicinebusinessStroke

description

The new short life isotope 195mAu has some suitable features for quantitative cerebral blood flow mapping. Its half-life is 30.5 s; therefore an injection can be repeated after 3 min (six half-lives) without any need for background subtraction and with the same specific activity. The calculated whole body radiation dose after three successive administrations of 25 mCi 195mAu amounts to 50 mrad. In comparison to a 99mTc pertechnetate injection it is estimated that the dose to the patients is reduced by a factor of eight (Garcia et al. 1981).

yearjournalcountryeditionlanguage
1985-01-01
https://doi.org/10.1007/978-3-642-70054-5_33