6533b851fe1ef96bd12aa207

RESEARCH PRODUCT

Utility of Procalcitonin for Diagnosis of Superimposed Infections in Patients With Acute Heart Failure.

Anna MollarJulio N #Xfa #XfezMaria Pilar VillanuevaJorge GuijarroGema Mi #Xfana

subject

Calcitoninmedicine.medical_specialtyCalcitonin Gene-Related Peptide030204 cardiovascular system & hematologyControlled studiesInfectionsProcalcitonin03 medical and health sciences0302 clinical medicineAntibiotic therapyMedicineHumansIn patientProtein PrecursorsIntensive care medicineHeart Failurebusiness.industryGeneral Medicinemedicine.diseaseAnti-Bacterial AgentsPneumonia030220 oncology & carcinogenesisHeart failureCardiology and Cardiovascular MedicinebusinessBiomarkers

description

Respiratory infections are well-known precipitant factors for heart failure decompensations. Nevertheless, the diagnosis of life-threatening infections, such as pneumonia, is challenging. Pneumonia and acute heart failure often display overlapping clinical findings and, in other cases, more accurate infection-related findings are missing. In recent years, procalcitonin has emerged as a promising tool for early and accurate diagnosis of pneumonia and, interestingly, for guiding antibiotic therapy in patients with acute heart failure. We discuss two cases of acute heart failure with high procalcitonin on admission and different clinical outcomes. In this setting, procalcitonin may be a useful tool for guiding antibiotic therapy. Further controlled studies are warranted.

10.3909/ricm0824https://pubmed.ncbi.nlm.nih.gov/28144023