6533b851fe1ef96bd12aa2a9
RESEARCH PRODUCT
Determination of diphenhydramine hydrochloride by flow injection with Bromophenol Blue and turbidimetric measurement
A. Sanchez SampedroS. Navasquillo SarrionJ. Martínez Calatayudsubject
ChromatographyDiphenhydramine hydrochlorideCalibration curveDiphenhydramineBromophenol blueBiochemistryAnalytical Chemistrychemistry.chemical_compoundDiphenhydraminechemistryNephelometry and TurbidimetryReagentElectrochemistrymedicineEnvironmental ChemistryIndicators and ReagentsBromphenol BlueSpectroscopymedicine.drugdescription
The study of a number of diphenhydramine-dye systems was carried out in order to determine the most suitable precipitate for the turbidimetric determination of diphenhydramine using flow injection (FI). The reagent selected was Bromophenol Blue. The chemical and FI variables were optimised. The calibration graph was linear over the concentration range 50-230 p.p.m. of diphenhydramine hydrochloride. A number of interfering substances were also investigated.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-06-01 | The Analyst |