6533b852fe1ef96bd12aa336

RESEARCH PRODUCT

MUC1 in human testis and ejaculated spermatozoa and its relationship to male fertility status.

Nicolás GarridoAntonio PellicerJosé RemohíMarcos MeseguerJosé Antonio Martínez-conejeroCarlos Simón

subject

MaleEjaculationmedia_common.quotation_subjectFertilityTesticleBiologydigestive systemAndrologyTestismedicineHumansEjaculationskin and connective tissue diseasesneoplasmsMUC1media_commonAzoospermiaReproductive functionMucin-1Obstetrics and GynecologySpermSpermatozoabiological factorsdigestive system diseasesmedicine.anatomical_structureFertilityReproductive MedicineReproductionGerm cell

description

MUC1 is a cell surface glycoprotein with a previously described antiadhesive role involved in different aspects of reproductive function. We found MUC1 expressed in male germ cell line and within the ejaculated sperm, but its presence in mature sperm does not seem to be related to male fertility. This was confirmed after analysis of results from assisted reproduction techniques with oocyte donation related with MUC1, although higher MUC1 expression is related to sperm recovery after preparation.

10.1016/j.fertnstert.2007.06.104https://pubmed.ncbi.nlm.nih.gov/17936281