6533b852fe1ef96bd12aaa5e
RESEARCH PRODUCT
A new method for the regioselective synthesis of β-enamino acid derivatives
Raquel Pérez CarlónSantos FusteroMa Dolores Díazsubject
chemistry.chemical_compoundchemistryOrganic ChemistryDrug DiscoveryNucleophilic substitutionImidazoleRegioselectivitychemistry.chemical_elementBoronBiochemistryCarbonylationCombinatorial chemistryCatalysisdescription
Abstract A mild, simple and efficient route to β-enamino imidazole carbonilic derivatives 3 by reaction of ketimines with N,N′ -carbonyl diimidazole in the presence of boron triflouride as catalyst has been developed. The conversion of 3 to esters has also been explored.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-01-01 | Tetrahedron Letters |