0000000000347180

AUTHOR

Ma Dolores Díaz

showing 3 related works from this author

A new and expeditious strategy for the synthesis of β-amino acids from Δ2-oxazolines

2001

Abstract A new, mild two-step synthesis of racemic β-amino acids starting from 2-alkyl-Δ2-oxazolines is described. The process implies the initial formation of masked N-substituted or N-unsubstituted β-enamino acid derivatives followed by chemoselective reduction of the enamino moiety. The process takes place with high yields, total chemoselectivity and moderate diastereoselectivity.

chemistry.chemical_classificationChemistryOrganic ChemistryDrug DiscoveryMoietyOrganic chemistryChemoselectivityBiochemistryAmino acidTetrahedron
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A new method for the regioselective synthesis of β-enamino acid derivatives

1993

Abstract A mild, simple and efficient route to β-enamino imidazole carbonilic derivatives 3 by reaction of ketimines with N,N′ -carbonyl diimidazole in the presence of boron triflouride as catalyst has been developed. The conversion of 3 to esters has also been explored.

chemistry.chemical_compoundchemistryOrganic ChemistryDrug DiscoveryNucleophilic substitutionImidazoleRegioselectivitychemistry.chemical_elementBoronBiochemistryCarbonylationCombinatorial chemistryCatalysisTetrahedron Letters
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ChemInform Abstract: A New Method for the Regioselective Synthesis of β-Enamino Acid Derivatives.

2010

Abstract A mild, simple and efficient route to β-enamino imidazole carbonilic derivatives 3 by reaction of ketimines with N,N′ -carbonyl diimidazole in the presence of boron triflouride as catalyst has been developed. The conversion of 3 to esters has also been explored.

chemistry.chemical_compoundchemistryRegioselectivityImidazolechemistry.chemical_elementGeneral MedicineBoronCombinatorial chemistryCatalysisChemInform
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