6533b852fe1ef96bd12aaeb1

RESEARCH PRODUCT

Application of model quality evaluation to systems biology

P. FalugiLaura Giarre

subject

Computer sciencemedia_common.quotation_subjectSystems biologyset membershipPopulationViral quasispeciesInterval (mathematics)Computational biologycomputer.software_genreSettore ING-INF/04 - AutomaticaModels of DNA evolutionmolecular biophysicsQuality (business)educationgenetics microorganismsmedia_commoneducation.field_of_studyDNA; biochemistry evolution (biological); genetics microorganisms; molecular biophysics; reaction kinetics; identification; set membership; optimizationBasis (linear algebra)Estimation theoryDNADNA biochemistry evolution (biological) genetics microorganisms molecular biophysics reaction kinetics identification set membership optimizationbiochemistry evolution (biological)identificationreaction kineticsData miningcomputeroptimization

description

Application of model quality evaluation to the quasispecies models is presented. These models are useful for the analysis of the DNA and RNA evolution and for the description of the population dynamics of viruses and bacteria. An estimate of the parameters together with their interval of variability is computed and the quality evaluation is tested on the basis of the model prediction error capability.

10.1109/isccsp.2008.4537206http://hdl.handle.net/10447/39011