6533b852fe1ef96bd12ab589

RESEARCH PRODUCT

ChemInform Abstract: Ternary Complexes of Cimetidine and Phenobarbital with Cu(II) in Methanolic Solution.

Joaquín BorrásR. OrtizH. JiménezL. Perelló

subject

chemistry.chemical_compoundchemistryStability constants of complexesInorganic chemistrymedicinePhenobarbitalGeneral MedicineMethanolCimetidineTernary operationmedicine.drugNuclear chemistry

description

The formation constants of the binary complexes Cu(CM)2+ and Cu(CM) 2 2+ as well as those of the ternary complexes Cu(CM)L + and Cu(CM)2 L + (CM=Cimetidine=N-Cyano-N′-methyl-N″[(5-methyl-1H-imidazol-4-yl)methyltioethyl]-guanidine; HL=Phenobarbital=5-ethyl-5-phenyl-barbituric acid) have been determined in 0.1 and 1.0 mol dm−3 NaClO4 methanol solutions at 25±0.2°C. The values of logX, log βstat.., and Δ logK confirm the stability of the ternary complexes.

https://doi.org/10.1002/chin.198634090