6533b852fe1ef96bd12ab6c1
RESEARCH PRODUCT
The “nitrogen effect” : Complexation with macrocycles potentiates fused heterocycles to form halogen bonds in competitive solvents
Kwaku TwumSanaz NadimiFrank Boateng OseiRakesh PuttreddyYvonne Bessem OjongJohn J. HaywardKari RissanenJohn F. TrantNgong Kodiah Beyehsubject
halogeenitkemiaOrganic ChemistryN-Heterocyclesdimeric capsulesmolekyylitGeneral ChemistryBiochemistrytyppiresorcinareneshalogen bondternary assembliesorgaaniset yhdisteetliuottimetdescription
Weak intermolecular forces are typically very difficult to observe in highly competitive polar protic solvents as they are overwhelmed by the quantity of competing solvent. This is even more challenging for three-component ternary assemblies of pure organic compounds. In this work, we overcome these complications by leveraging the binding of fused aromatic N-heterocycles in an open resorcinarene cavity to template the formation of a three-component halogen-bonded ternary assembly in a protic polar solvent system. peerReviewed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2023-02-07 |