6533b852fe1ef96bd12ab915
RESEARCH PRODUCT
The selective synthesis of metallanucleosides and metallanucleotides: a new tool for the functionalization of nucleic acids.
Miguel A. SierraMamen Martín-ortizMar Gómez-gallegoCarmen Ramírez De Arellanosubject
Base pairMetalationchemistry.chemical_elementIridiumCatalysisNucleobaseRhodiumchemistry.chemical_compoundNucleic AcidsOrganic chemistryRhodiumBase PairingPurine NucleotidesBase SequenceChemistryOrganic ChemistryRNAGeneral ChemistryDNAPurine NucleosidesCombinatorial chemistryMetalsNucleic acidSurface modificationRNADNAdescription
Nucleobases team up: the efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having M-C bonds (M=Ir(III), Rh(III)) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-08-30 | Chemistry (Weinheim an der Bergstrasse, Germany) |