0000000000343941

AUTHOR

Mamen Martín-ortiz

showing 6 related works from this author

On the Use of Metal Purine Derivatives (M=Ir, Rh) for the Selective Labeling of Nucleosides and Nucleotides

2014

The reactions of neutral or cationic IrIII and RhIII derivatives of phenyl purine nucleobases with unsymmetrical alkynes produce new metallacycles in a predictable manner, which allows for the incorporation of either photoactive (anthracene or pyrene) or electroactive (ferrocene) labels in the nucleotide or nucleoside moiety. The reported methodology (metalation of the purine derivative and subsequent marker insertion) could be used for the postfunctionalization and unambiguous labeling of oligonucleotides.

PurineMetalationIridiumCatalysisNucleobasechemistry.chemical_compoundOrganometallic CompoundsOrganic chemistryMoietyRhodiumNucleotideNuclear Magnetic Resonance BiomolecularPurine NucleotidesAnthraceneschemistry.chemical_classificationPyrenesMolecular StructureOrganic ChemistryCationic polymerizationPurine NucleosidesGeneral ChemistryCombinatorial chemistryFerrocenechemistryAlkynesNucleosideChemistry - A European Journal
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The selective synthesis of metallanucleosides and metallanucleotides: a new tool for the functionalization of nucleic acids.

2012

Nucleobases team up: the efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having M-C bonds (M=Ir(III), Rh(III)) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.

Base pairMetalationchemistry.chemical_elementIridiumCatalysisNucleobaseRhodiumchemistry.chemical_compoundNucleic AcidsOrganic chemistryRhodiumBase PairingPurine NucleotidesBase SequenceChemistryOrganic ChemistryRNAGeneral ChemistryDNAPurine NucleosidesCombinatorial chemistryMetalsNucleic acidSurface modificationRNADNAChemistry (Weinheim an der Bergstrasse, Germany)
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CCDC 952797: Experimental Crystal Structure Determination

2014

Related Article: Marta Valencia, Mamen Martín-Ortiz, Mar Gómez-Gallego, Carmen Ramírez de Arellano, Miguel A. Sierra|2014|Chem.-Eur.J.|20|3831|doi:10.1002/chem.201304091

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(eta^5^-Pentamethylcyclopentadienyl)-(eta^2^-4-(2-(9-methyl-9H-purin-6-yl)phenyl)-13-diphenylbuta-13-dien-2-yl)-iridium hexafluorophosphate
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CCDC 952795: Experimental Crystal Structure Determination

2014

Related Article: Marta Valencia, Mamen Martín-Ortiz, Mar Gómez-Gallego, Carmen Ramírez de Arellano, Miguel A. Sierra|2014|Chem.-Eur.J.|20|3831|doi:10.1002/chem.201304091

Space GroupCrystallographyCrystal System(eta^5^-Pentamethylcyclopentadienyl)-(1-(anthracen-9-yl)-3-methoxy-1-[2-(9-methyl-9H-purin-6-yl)phenyl]-3-oxoprop-1-en-2-yl)-chloro-rhodium dichloromethane solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 952796: Experimental Crystal Structure Determination

2014

Related Article: Marta Valencia, Mamen Martín-Ortiz, Mar Gómez-Gallego, Carmen Ramírez de Arellano, Miguel A. Sierra|2014|Chem.-Eur.J.|20|3831|doi:10.1002/chem.201304091

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(eta^5^-Pentamethylcyclopentadienyl)- acetonitrile-(2-(9-methyl-9H-purin-6-yl)phenyl)-iridium hexafluorophosphate
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CCDC 952794: Experimental Crystal Structure Determination

2014

Related Article: Marta Valencia, Mamen Martín-Ortiz, Mar Gómez-Gallego, Carmen Ramírez de Arellano, Miguel A. Sierra|2014|Chem.-Eur.J.|20|3831|doi:10.1002/chem.201304091

Space GroupCrystallographyCrystal System(eta^5^-Pentamethylcyclopentadienyl)-chloro-(3-methoxy-2-(2-(9-methyl-9H-purin-6-yl)phenyl)-3-oxo-1-phenylprop-1-en-1-yl)-iridium unknown solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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