6533b853fe1ef96bd12abf16

RESEARCH PRODUCT

False-Positive LSD Drug Screening Induced by a Mucolytic Medication

Gerd HafnerThomas KernJ. RöhrichWinfried PrellwitzJohannes LotzS. Zörntlein

subject

Drugmedicine.diagnostic_testbusiness.industrymedia_common.quotation_subjectBiochemistry (medical)Clinical BiochemistryPharmacologyClinical routineCraniocerebral traumaHomogeneousImmunoassaymedicineIngestionAmphetaminebusinessmedicine.drugmedia_commonLysergic acid diethylamide

description

Since the early 1990s, the ingestion of lysergic acid diethylamide (LSD) as an inexpensive alternative to amphetamine derivatives has once again become widespread (1)(2). Consequently, screening of LSD has gained importance in clinical routine. The drug screening of a patient with a severe craniocerebral trauma showed a positive LSD screening by the homogeneous immunoassay CEDIA® DAU LSD (Boehringer Mannheim). In spite of the 3-h half-life of LSD in plasma (3), the drug screening remained positive for several days. These samples …

https://doi.org/10.1093/clinchem/44.7.1580a