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RESEARCH PRODUCT
ADR1 and SNF1 Mediate Different Mechanisms in Transcriptional Regulation of Yeast POT1 Gene
J. C. IgualBeatriz Navarrosubject
Transcription GeneticRecombinant Fusion ProteinsGenes FungalBiophysicsSaccharomyces cerevisiaeBiologyMicrobodiesBiochemistryTranscription (biology)Gene Expression Regulation FungalGene expressionTranscriptional regulationAcetyl-CoA C-AcetyltransferaseLuciferasesMolecular BiologyGeneDerepressionRegulation of gene expressionGeneticsfungiGene Transfer TechniquesCell BiologyYeastCulture MediaCell biologycarbohydrates (lipids)GlucoseStationary phaseMutationProtein Kinasesdescription
We studied the consequences of adr1 and snf1 mutations on POT1 gene expression in different growth conditions. The results obtained reveal that ADR1 and SNF1 genes affect POT1 transcription in different ways: ADR1 has a minor role in derepression in low concentration of glucose but is essential for activation in stationary phase whereas SNF1 is essential for derepression and activation, although it does not seem to be directly involved in the molecular mechanism of activation in stationary phase.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-07-01 | Biochemical and Biophysical Research Communications |