6533b853fe1ef96bd12ac1f7

RESEARCH PRODUCT

Endoscopic near infrared and indocyanine green to verify the viability of the subcutaneous flap for vulvar cancer.

Alessandra CiancioloGiulia GambinoGiulio SozziRoberto BerrettaMartina PuglieseValentina CeniVito Andrea Capozzi

subject

0301 basic medicineIndocyanine Greenmedicine.medical_specialtySurgical Flaps03 medical and health scienceschemistry.chemical_compound0302 clinical medicineMedicineHumansAgedSpectroscopy Near-InfraredVulvar Neoplasmsbusiness.industryWound dehiscenceObstetrics and GynecologyInguinal lymphadenopathyVulvar cancerPlastic Surgery Proceduresmedicine.diseaseLateral marginSurgery030104 developmental biologyOncologychemistry030220 oncology & carcinogenesisRadical VulvectomyCarcinoma Squamous CellLymph Node ExcisionVulvectomyFemaleFlap necrosismedicine.symptombusinessIndocyanine greenSurgical site infection

description

Abstract Introduction Vulvar cancer often requires radical vulvectomy with subsequent vulvar flap. Approximately in 20–60% of cases, there are post-operative complications ranging from infection to flap necrosis that often require reoperation. Several methods have been described to verify the vitality of the flap, but these are often expensive and require specific machinery that is not generally present in a gynecological clinic. In this case report, we present a viability verification of V Y fasciocutaneous advancement flap for vulvar reconstruction by Endoscopic Near-Infrared and Indocyanine Green. Methodology The patient was a 67-year-old woman with FIGO IB ≤ 4 cm squamous cell vulvar cancer with absence of inguinal lymphadenopathy. The lesion appeared about 35 mm from the lateral margin of the large left lip and extended to the left inguinocrural fold. The patient underwent left inguinal lymphadenectomy and left radical hemivulvectomy with a left fasciocutaneous medial-thigh advancement flap. For the flap evaluation, we endovenous administered 50 mg of Indocyanine Green diluted in 10 ml of saline solution. After 10 min we visualized the flap margin with a near-infrared laparoscopic view. The evaluation was repeated at the end of the surgical procedure and we confirmed the good vascularization of the flap. Results No early or late post-operative complications were obtained. There was no wound dehiscence, marginal necrosis or surgical site infection. Conclusions Verifying the viability of the vulvar flap using near-infrared laparoscopic optics was easy to use, reproducible and highly economical technique. This could be a reproducible alternative to other more expensive techniques.

10.1016/j.ygyno.2019.06.018https://pubmed.ncbi.nlm.nih.gov/31266656