6533b853fe1ef96bd12ac222

RESEARCH PRODUCT

Endoscopic enhancement of the healing of high-risk colon anastomoses by low-power helium-neon laser. An experimental study.

Vicente Garcia-fonsJose Vidal-martinezFrancisco Asencio-aranaErnesto Molina-andreuF Martinez-soriano

subject

Malemedicine.medical_specialtyColonAnastomosisRadiation Dosagelaw.inventionHydroxyprolinechemistry.chemical_compoundSurgical anastomosislawRisk FactorsTensile StrengthSurgical Wound DehiscencemedicineAnimalsIrradiationWound Healingbusiness.industryAnastomosis SurgicalGastroenterologyRats Inbred StrainsGeneral MedicineColonoscopyLaserSurgeryRatschemistryHelium/neon laserCollagenLaser TherapyWound healingNuclear medicinebusinessBursting strength

description

Recent studies suggest that helium-neon (He-Ne) lasers at low energy can enhance wound healing in intestinal anastomoses. In this experimental study, we tested the strength and collagen concentration of high-risk anastomoses of the rat colon after endoscopic irradiation by helium-neon laser. Our results show that repeated helium-neon laser irradiation (1.9 J/cm 2)increases the bursting strength of the anastomoses by almost 100% on the fourth postoperative day. This effect is not observed by increasing the radiation dose (6.4 J/cm 2).Differences in collagen (hydroxyproline) concentration did not reach statistical significance.

yearjournalcountryeditionlanguage
1992-06-01Diseases of the colon and rectum
10.1007/bf02050537https://pubmed.ncbi.nlm.nih.gov/1587175