6533b853fe1ef96bd12ac286
RESEARCH PRODUCT
Upconversion nanoparticles with a strong acid-resistant capping
Nestor EstebanezIleana B. RecaldeLaura Francés-sorianoMarta LirasMaría González-béjarJulia Pérez-prietosubject
DenticityMaterials science02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnologyGraftingBiocompatible material01 natural scienceshumanities0104 chemical sciencesUpconversion nanoparticleschemistry.chemical_compoundchemistryPh rangeCopolymerOrganic chemistryGeneral Materials SciencePhotosensitizer0210 nano-technologyMethylene blueNuclear chemistrydescription
Water-dispersible upconversion nanoparticles (β-NaYF:Yb,Er, UCNP) coated with a thin shell of a biocompatible copolymer comprising 2-hydroxyethylmethacrylate (HEMA) and 2-acrylamido-2-methyl-1-propanesulphonsulphonic acid (AMPS), which we will term COP, have been prepared by multidentate grafting. This capping is remarkably resistant to strong acidic conditions as low as pH 2. The additional functionality of the smart UCNP@COP nanosystem has been proved by its association to a well-known photosensitizer (namely, methylene blue, MB). The green-to-red emission ratio of the UC@COP@MB nanohybrid exhibits excellent linear dependence in the 7 to 2 pH range as a consequence of the release of the dye as the pH decreases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-03-18 |