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RESEARCH PRODUCT
Dietary therapy and non-surgical periodontal treatment in obese patients with chronic periodontitis.
Antonio Hernández-mijaresCelia BañulsMilagros RochaMayte Martinez-herreraSandra López-domènechFrancisco J. SilvestreJavier Silvestre-rangilsubject
medicine.medical_specialtyDiet therapy030209 endocrinology & metabolismSystemic inflammationGastroenterology03 medical and health sciences0302 clinical medicineWeight lossInternal medicinePeriodontal Attachment LossWeight LossMedicineHumansObesityPeriodontitisComplement component 3business.industry030206 dentistryAnthropometrymedicine.diseaseChronic periodontitisObesitySpainChronic PeriodontitisPeriodonticsmedicine.symptomPeriodontal Indexbusinessdescription
Aim The effect of dietary weight loss intervention on periodontal therapy is unknown. Therefore, we aimed to evaluate whether weight loss improves the response of obese subjects to non-surgical periodontal treatment. Materials and methods This interventional study in obese patients was conducted at the University Hospital Dr. Peset (Valencia, Spain). Patients were divided into two groups with and without dietary therapy. All participants received non-surgical periodontal treatment. Periodontal, anthropometric and biochemical parameters were assessed at baseline and 12 weeks. Results A total of 78 patients were re-evaluated after intervention. All periodontal parameters improved in both groups after periodontal treatment, but the reductions in mean probing depth (PD) (0.23 mm vs. 0.12 mm) and in percentage of sites with PD 4-5 mm (10.4% vs. 5.89%) were significantly higher in the dietary group. Additionally, complement component 3 (C3) and tumour necrosis factor alpha (TNFα) decreased in the dietary group after intervention. Percentage of change in mean PD correlated with change in C3 (r = 0.233, p = 0.043), and percentage of change in sites with PD 4-5 mm correlated with change in TNFα (r = 0.414, p = 0.012). Conclusions This study suggests that dietary weight loss intervention causes a greater reduction in systemic inflammation, which may enhance the response to periodontal treatment.
year | journal | country | edition | language |
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2018-01-27 | Journal of clinical periodontology |