Inhibitory Effects of Various Extracts of Argentine Plant Species on Free-radical-mediated Reactions and Human Neutrophil Functions

6533b853fe1ef96bd12acad3

RESEARCH PRODUCT

Inhibitory Effects of Various Extracts of Argentine Plant Species on Free-radical-mediated Reactions and Human Neutrophil Functions

Liliana Muschietti S. Debenedetti Graciela Ferraro Miguel Payá Adriana M. Broussalis O. Hnatyszyn Virginia Martino M. Silla E. Vayá J.d. Coussio María José Alcaraz

subject

Pharmacology Antioxidant Superoxide medicine.medical_treatment Degranulation Biological activity Pterocaulon Biology biology.organism_classification Lipid peroxidation chemistry.chemical_compound chemistry Biochemistry Microsoma medicine Microsome

description

Extracts of Argentine plant species used in folk medicine were evaluated for their antioxidant properties and ability to influence human neutrophil functions, including superoxide anion release and degranulation. The infusion and methanol extract of Achyrocline flaccida, and the infusion of Pterocaulon polystachium exhibited chain-breaking antioxidant activity in Fe 2+ /ascorbate-induced lipid peroxidation of rat liver microsomal fractions and scavenged peroxyl radicals in an aqueous assay system. Nevertheless their superoxide scavenging ability was lower. The dichloromethane extracts of Phyllanthus sellowianus, Achyrocline flaccida, Gamochaeta simplicicaulis, Pterocaulon polystachium and Eupatorium buniifolium, besides the infusion of Eupatorium buniifolium and the methanol extract of Pterocaulon polystachium, inhibited neutrophil functions.

year	journal	country	edition	language
1996-05-01	Phytotherapy Research

https://doi.org/10.1002/(sici)1099-1573(199605)10:3<228::aid-ptr823>3.0.co;2-l

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