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RESEARCH PRODUCT

Risk Perception and Psychological Distress in Genetic Counselling for Hereditary Breast and/or Ovarian Cancer

G. Lo CocoR De LucaDaniele FanaleValentina CalòPatrizia DorangricchiaAntonio RussoCinzia GuarnacciaGiuseppe Cicero

subject

Adult0301 basic medicinemedicine.medical_specialtygenetic structuresmedia_common.quotation_subjectGenetic counseling[SHS.PSY]Humanities and Social Sciences/PsychologyBreast NeoplasmsGenetic CounselingAnxiety030105 genetics & heredityHospital Anxiety and Depression Scale[SHS]Humanities and Social Sciences[SHS.PSY] Humanities and Social Sciences/Psychology03 medical and health sciences0302 clinical medicineRisk FactorsPerceptionmedicineHumansGenetic Predisposition to DiseaseDistrePsychiatryGenetics (clinical)Depression (differential diagnoses)BRCA 1/2media_commonOvarian NeoplasmsGenetic counsellingDistressCancerMiddle Agedmedicine.diseaseCancer risk perception3. Good healthRisk perceptionDistress030220 oncology & carcinogenesisMutationAnxietyFemalePerception[SHS] Humanities and Social SciencesGenetic risk perceptionmedicine.symptomPsychologyStress PsychologicalClinical psychology

description

International audience; Oncological Genetic Counselling (CGO) allows the identification of a genetic component that increases the risk of developing a cancer. Individuals' psychological reactions are influenced by both the content of the received information and the subjective perception of their own risk of becoming ill or being a carrier of a genetic mutation. This study included 120 participants who underwent genetic counselling for breast and/or ovarian cancer. The aim of the study was to examine the relation between their cancer risk perception and the genetic risk during CGO before receiving genetic test results, considering the influence of some psychological variables, in particular distress, anxiety and depression. Participants completed the following tools during a psychological interview: a socio-demographic form, Cancer Risk Perception (CRP) and Genetic Risk Perception (GRP), Hospital Anxiety and Depression Scale (HADS) and Distress Thermometer (DT). The data seem to confirm our hypothesis. Positive and significant correlations were found between the observed variables. Moreover, genetic risk perception determined an increase in depressive symptomatology and cancer risk perception led to an increase in anxious symptomatology, specifically in participants during cancer treatment. The present results suggest the importance of assessing genetic and cancer risk perception in individuals who undergo CGO, to identify those who are at risk of a decrease in psychological well-being and of developing greater psychological distress.

yearjournalcountryeditionlanguage
2017-10-01
https://hal.univ-rennes2.fr/hal-01988393