6533b853fe1ef96bd12ad4a0

RESEARCH PRODUCT

Pathophysiology of respiratory failure

Francisco Javier BeldaMarina SoroCarlos Ferrando

subject

Anesthesiology and Pain MedicineRespiratory failurebusiness.industryAnesthesiamedicinemedicine.symptomRespiratory systemCritical Care and Intensive Care MedicinebusinessHypercapniaPathophysiologyrespiratory tract diseases

description

Summary Respiratory failure (RF) is defined as a disturbance in gas exchange in the respiratory system which produces in arterial BGA a PaO 2 2  > 50 mmHg (hypercapnia). However hypoxaemic normocapnic (or hypocapnic) RF due to the failure in gas exchange is very common and should be separated from mechanical RF. Respiratory failure (hypercapnic) with or without hypoxaemia related to a failure in the respiratory pump. This review is focused on the pathophysiology of the mechanical RF less well known amongst anaesthesiologists.

https://doi.org/10.1016/j.tacc.2013.05.003