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RESEARCH PRODUCT

A Computational Study on Temperature Variations in MRgFUS Treatments Using PRF Thermometry Techniques and Optical Probes

Giorgio Ivan RussoFabrizio VicariCarmelo MilitelloGiovanni BorasiLuca AgnelloLeonardo RundoSalvatore Vitabile

subject

Optical fiberMaterials scienceInterferometric optical fibers MRgFUS Proton resonance frequency shift RBF neural networks Referenceless thermometry Temperature variationslcsh:Computer applications to medicine. Medical informaticsImaging phantomlcsh:QA75.5-76.95Article030218 nuclear medicine & medical imaginglaw.invention03 medical and health sciencesinterferometric optical fibers0302 clinical medicinelawMedical imagingRadiology Nuclear Medicine and imaginglcsh:PhotographyElectrical and Electronic EngineeringReferenceless ther-mometryProton resonance frequencytemperature variationsbusiness.industryMRgFUSUltrasoundproton resonance frequency shiftFocused ultrasound surgerylcsh:TR1-1050Computer Graphics and Computer-Aided DesignRBF neural networksClinical PracticeInterferometryreferenceless thermometrylcsh:R858-859.7Computer Vision and Pattern Recognitionlcsh:Electronic computers. Computer sciencebusiness030217 neurology & neurosurgeryInterferometric optical fibers; MRgFUS; Proton resonance frequency shift; RBF neural networks; Referenceless ther-mometry; Temperature variationsBiomedical engineering

description

Structural and metabolic imaging are fundamental for diagnosis, treatment and follow-up in oncology. Beyond the well-established diagnostic imaging applications, ultrasounds are currently emerging in the clinical practice as a noninvasive technology for therapy. Indeed, the sound waves can be used to increase the temperature inside the target solid tumors, leading to apoptosis or necrosis of neoplastic tissues. The Magnetic resonance-guided focused ultrasound surgery (MRgFUS) technology represents a valid application of this ultrasound property, mainly used in oncology and neurology. In this paper

10.3390/jimaging7040063http://europepmc.org/articles/PMC8321332