6533b853fe1ef96bd12ad7ee

RESEARCH PRODUCT

Spectrophotometric determination of promazine with an oxidative column in FIA manifolds

Anatol KojłoHelena Puzanowska-tarasiewiczJ. Martínez Calatayud

subject

AnalyteChemistry PharmaceuticalClinical BiochemistryRelative standard deviationPharmaceutical Sciencechemistry.chemical_elementManganesePharmaceutical formulationRedoxDosage formAnalytical ChemistryDrug DiscoverymedicinePromazineSpectroscopyPromazineFlow injection analysisManganeseChromatographyChemistryOxidesHydrogen-Ion ConcentrationManganese CompoundsCalibrationFlow Injection AnalysisSpectrophotometry UltravioletOxidation-Reductionmedicine.drug

description

Abstract A simple flow-injection spectrophotometric method for the determination of promazine is described. The two proposed procedures are based on the oxidation of analyte with a manganese dioxide column. Concentrations of promazine in the ranges 2–20 and 1–6 are determined with a relative standard deviation of 1.0%. The injection rates are 62 and 80 samples h −1 , respectively. The influence of foreign species and the determination of promazine in a pharmaceutical formulation are also reported.

yearjournalcountryeditionlanguage
1992-10-01Journal of Pharmaceutical and Biomedical Analysis
https://doi.org/10.1016/0731-7085(91)80081-j