6533b854fe1ef96bd12adf1b

RESEARCH PRODUCT

Two laboratory-confirmed cases of Japanese encephalitis imported to Germany by travelers returning from Southeast Asia

August StichPetra EmmerichJonas Schmidt-chanasitDennis TappeGerhard DoblerAndrea NemecekFrauke ZippMartin GabrielStephan Günther

subject

MaleVeterinary medicineDestinationsAntibodies ViralSoutheast asiaGermanyVirologyHumansMedicineEncephalitis JapaneseSocioeconomicsAgedTravelbiologybusiness.industryMiddle AgedJapanese encephalitisThailandbiology.organism_classificationClinical diseasemedicine.diseaseVaccinationFlavivirusInfectious DiseasesImmunoglobulin MIndonesiaImmunoglobulin GFemalebusinesshuman activitiesEncephalitis

description

Japanese encephalitis virus is the leading cause of encephalitis in Asia and parts of the Pacific. Despite the high number of symptomatic infections in endemic countries, clinical disease in travelers is rare. However, an increasing number of imported infections from popular holiday destinations in Southeast Asia have been recorded in the past few years, including serious disease courses in short-term travelers. Here we report two severe, non-fatal cases in tourists, who returned from a long-time stay in Thailand and a short-term trip to Bali, Indonesia, respectively. Recommendations for vaccination and pre-travel advice are discussed.

https://doi.org/10.1016/j.jcv.2012.03.004