6533b854fe1ef96bd12ae078
RESEARCH PRODUCT
Mathematical simulation of Doppler changes in late-onset smallness; progression patterns of cerebral and umbilical anomalies define two types of late-onset fetal growth restriction.
Silvia BuongiornoBenjamin-remigio Villarroya AlfonsoJosé Morales-rosellóJosé Morales-rosellóGabriela LoscalzoDavid Hervas-marínAlfredo Perales-marínAlfredo Perales-marínsubject
medicine.medical_specialtyLate onset030204 cardiovascular system & hematologyUltrasonography PrenatalUmbilical Arteries03 medical and health sciencessymbols.namesake0302 clinical medicineFetusPregnancyInternal medicinemedicineFetal growthHumansreproductive and urinary physiologyFetus030219 obstetrics & reproductive medicineFetal Growth Retardationbusiness.industryHemodynamicsInfant NewbornObstetrics and GynecologyUltrasonography Dopplermedicine.diseaseembryonic structuresPediatrics Perinatology and Child HealthInfant Small for Gestational Agecardiovascular systemsymbolsCardiologySmall for gestational ageFemalebusinessDoppler effectcirculatory and respiratory physiologyMathematical simulationdescription
To evaluate the progression of Doppler abnormalities in fetuses with late-onset fetal smallness (SGA) that become growth restricted (FGR).524 Doppler examinations of the umbilical and cerebral arteries systems, belonging to 442 late-onset SGA fetuses after week 34, were studied, evaluating by means of the statistical difference with the respective abnormal centiles, the pattern of progression into abnormal Doppler values and the distribution and cumulative sum of Doppler anomalies according to the interval to delivery.Only one third (33.5%,Two thirds of late-onset fetal smallness occurs without hemodynamic changes. In half of the remaining cases an initial cerebral vasodilation defines a group of fetuses with similar outcome but higher BW centile.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-09-26 | The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |