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RESEARCH PRODUCT
Vestibular compensation in cerebellar stroke patients.
F. RhodeMarianne DieterichNotger G. MüllerBernhard Baiersubject
MaleCerebellumInhibitory postsynaptic potentialCerebellar Diseasesphysiopathology [Vestibule Labyrinth]otorhinolaryngologic diseasesMedicineCerebellar strokeHumansIn patientddc:610StrokeAgedVestibular systemChronic stagephysiopathology [Stroke]pathology [Cerebellar Diseases]business.industryMiddle AgedVestibular Function Testsmedicine.diseaseCerebellar lesionMagnetic Resonance Imagingphysiopathology [Cerebellar Diseases]Strokemedicine.anatomical_structurenervous systemNeurologypathology [Stroke]FemaleNeurology (clinical)Vestibule LabyrinthbusinessNeurosciencedescription
Background and purpose There is little evidence about the site where compensatory vestibular mechanisms in patients with cerebellar strokes take place. Methods To determine whether the location of a cerebellar lesion might be a crucial variable in vestibular compensation a sample of 22 patients with cerebellar stroke were tested for graviceptive function in the acute and chronic stage. Results Our statistical anatomical lesion analysis indicated that mainly lesions of the cerebellar hemispheres (lobule V, VI, VIIa) hinder vestibular compensation and might lead to an overcompensation. Conclusions Overcompensation-induced dysfunction can be explained by the absence of cerebellar inhibitory signals.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-06-19 | European journal of neurology |