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RESEARCH PRODUCT

Long-term consequences of polycystic ovary syndrome on cardiovascular risk

Giovam Battista RiniRizzo ManfrediKaspar BerneisEnrico CarminaGiatgen A. Spinas

subject

AdultPolycystic ovary syndrome cardiovascular risk menopause eventsAgingPediatricsmedicine.medical_specialty10265 Clinic for Endocrinology and Diabetology610 Medicine & healthBody weightDiabetes ComplicationsRisk FactorsmedicineHumansCystObesityAgedAged 80 and overGynecologyPostmenopausal womenbusiness.industryHyperandrogenismObstetrics and Gynecology2729 Obstetrics and Gynecology2743 Reproductive MedicineMiddle Agedmedicine.diseasePolycystic ovaryMenopauseC-Reactive ProteinIncreased riskReproductive MedicineCardiovascular DiseasesAndrogensFemaleAdiponectinHyperandrogenismbusinessBiomarkersVisceral ObesityPolycystic Ovary Syndrome

description

Most available data suggest that the prevalence of cardiovascular diseases in women with polycystic ovary syndrome (PCOS) is smaller than expected based on risk calculations during fertile years; therefore, more studies are needed on long-term cardiovascular consequences. Evidence is accumulating that postmenopausal women with PCOS have an increased risk of cerebrovascular events and cardiovascular morbidity. These events are partially related to persisting hyperandrogenism but are mostly correlated with excessive body weight (mainly visceral obesity); this suggests that our best long-term strategy is to ensure that women with PCOS are informed about their high risk for metabolic and cardiovascular diseases.

https://dx.doi.org/10.5167/uzh-17402